Criteria	Met by MCED testing
1. The condition sought should be an important health problem.	Yes
2. There should be an accepted treatment for patients with recognized disease.	Yes
3. Facilities for diagnosis and treatment should be available.	Yes, although access to specialized cancer centers may be limited for rare cancers
4. There should be a recognizable latent or early symptomatic stage.	Not established for all cancers detected via MCED testing
5. There should be a suitable test or examination.	Yes
6. The test should be acceptable to the population.	Blood testing is generally very acceptable; however, given the currently limited number of insurers covering MCED testing, it is unaffordable for many individuals
7. The natural history of the condition, including development from latent to declared disease, should be adequately understood.	Not for all cancers detected by MCED testing
8. There should be an agreed policy on whom to treat as patients.	Uncertain whether the test is appropriate for the general population versus individuals at higher risk for cancer
9. The cost of case finding (including diagnosis and treatment of patients diagnosed) should be economically balanced in relation to the possible expenditure on medical care as a whole.	Currently unknown
10. Case finding should be a continuing process and not a “once and for all” project.	Uncertain—the interval for repeat testing is not yet determined