TABLE 1.
Putative efflux pumps identified based on the genome sequence of Campylobacter jejuni NCTC11168
| Gene or gene cluster | Product description | Function | Efflux family | Size(s) (bp) | Nucleotide location in insertional mutant |
|---|---|---|---|---|---|
| Cj0035c | Putative efflux protein | Antibiotic resistance | MFS | 1,203 | 297 |
| Cj0309c-Cj0310c | Putative efflux protein | Drug/analogue sensitivity | DMT | 315/339 | 487 on Cj0310c |
| Cj0365c (cmeC)-Cj0366c (cmeB)-Cj0367c (cmeA) | Putative efflux system | Antibiotic resistance | RND | 1,479/3,123/1,104 | 1525 on Cj0366c |
| Cj0560 | Putative integral membrane protein | Multidrug | MATE | 1,329 | 612 |
| Cj0619 | Putative integral membrane protein | Multidrug | MATE | 1,317 | 571 |
| Cj1031 (cmeD)-Cj1032 (cmeE)- | Putative efflux system | Antibiotic resistance | RND | 1,275/741/3,018 | 159 on Cj1033 |
| Cj1033 (cmeF) | |||||
| Cj1173-Cj1174 | Putative efflux protein | Drug/analogue sensitivity | DMT | 342/309 | 381 on Cj1174 |
| Cj1241 | Transport/binding protein | Multidrug | MFS | 1,200 | 537 |
| Cj1257c | Putative efflux pump | Drug/analogue sensitivity | MFS | 1,185 | 556 |
| Cj1687 | Putative efflux protein | Antibiotic resistance | MFS | 1,272 | 679 |