Figure 8.

ARP1 alleles mapped on a predicted structure of the Arp1p filament. (a) Alleles are represented by number. arp1-94 is not indicated because it resides in the extreme N terminus, not represented in the structure. The “pointed-end” is up and the “barbed-end” is down in all images. Yellow indicates pseudo-wild type, orange indicates Ts^–, and red indicates Lethal. (b) The monomers in (a) are shown relative to the Arp1p filament. A schematic representation of the filament consisting of five boxes, each with a magenta inner face and teal outer face, serves as an orienting guide to the relative rotation of each filament.