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. 2005 Sep;16(9):4294–4303. doi: 10.1091/mbc.E04-12-1076

Figure 4.

Figure 4.

Cooperation of Rac and RhoA in the induction of membrane ruffles. (A) DIC and CFP images of HeLa cells expressing CFP-Rac-V12 alone, CFP-Rac-V12 with RhoA-V14, or CFP-Rac-V12 with RhoA-N19 are shown. The white arrows indicate the membrane ruffles in HeLa cells expressing only CFP-Rac-V12. Scale bars, 10 μm. (B) Cells exhibiting a ruffling phenotype were scored. Values are presented as percentages of the total number of transfected cells. Averaged data from five independent experiments, with an average of 10 cells scored per experiment, are shown with the SD.