Figure 1.

Time course of passively transferred EAAN. IgG was injected intraperitoneally on day 0. Data are expressed as mean with SEM (vertical bar). a, Rabbit IgG specific for ganglionic AChR was detectable in mouse plasma 3 weeks after injection. b, Body weight for each mouse is expressed relative to experimental day 0. Mice injected with ganglionic AChR IgG (filled circles) lose weight rapidly for several days and then regain weight. Asterisks indicate days at which their weights differed from control IgG recipient mice (open squares). ^*p < 0.01; ^**p < 0.0001. c, EAAN mice have marked urinary retention. Bladder size is expressed as weight of the bladder and its contents at autopsy. Mean bladder weight of control mice (solid horizontal line) and 95% confidence intervals (broken lines) are shown for comparison.