Figure 2.

Overt signs of EAAN. a, Pupils of mice receiving control IgG were constricted in response to light. Mice with EAAN (3 d after ganglionic AChR IgG injection) had dilated pupils that responded poorly to light. b, At autopsy on day 4 after injection, mice receiving control IgG have a normal appearing bowel and empty bladder (^*). Mice with EAAN show marked urinary retention (^*) and dilated loops of large and small bowel. The proximal small bowel is colored resulting from oral administration of blue dye 30 min before autopsy.