Table 1.

Analysis of PRODH Alleles

Allele	Reference SNP (rs) Number	Exon	Allele Frequency in Control Individualsa	Identified inb	Associated with Schizophreniac
Q19P	2008720	2	.29d	C, S
A167V		4	.03e	C, S
R185W	4819756	5	.37f	C, S
R185Q		5	.05f	C
L289M		8	.03f; 0/136g	C, H, S
P406L	3970555	11	0/216f	S
D426N		12	0/94e	H
V427M	2238731	12	.02f	C, H, S	+f
R431H	2904552	12	.16d; .10g; .13h	C, H, S
L441P	2904551	12	0/74f; 0/136g	H, S
R453C	3970559	12	.004f; .015g	C, H, S	+f
A455S	1807467	12	0/136g	H, S
T466M	2870984	12	0/156f	S	+f
A472T	2870983	12	.02f; .10g; .07h	C, S	+f
Q521R	450046	14	.05g	C, H, S
Q521E		14	0/94e

^aFrequency in controls, as determined by the indicated (footnoted) study. For alleles not detected, the result is presented as 0/number of chromosomes screened.

^bC=control individuals, H=hyperprolinemics, and S=schizophrenics.

^cAssociated with schizophrenia in at least one study, at P⩾.05.

^dWilliams et al. ^2003b.

^eThe present study.

^fLiu et al. 2002.

^gJacquet et al. ²⁰⁰².

^hJacquet et al. ²⁰⁰⁴.