Table A1.
Sequences of TaqMan and Invader Probes Used for Genotyping of IL4, IL13, and IL4RA SNPs[Note]
|
Sequence (5′→3′) |
|||
| Gene and dbSNP | Technology | Probe 1 | Probe 2 |
| IL4RA: | |||
| rs2057768 | TaqMan | CTGCTCCATCAGTC | CTGCTCCGTCAGTC |
| rs1805010 | TaqMan | CCACACGTGTATCC | CCACACGTGTGTCC |
| rs1805011 | Invader | CGCGCCGAGGTCCCTTCCCTCCTGG | ATGACGTGGCAGACGCCCTTCCCTCCTG |
| rs1805012 | TaqMan | TCACGCCTTCTTC | TCATGCCTTCTTCCAC |
| rs1805013 | Invader | ATGACGTGGCAGACCGGGAAGTACGAGTGC | CGCGCCGAGGTGGGAAGTACGAGTGC |
| rs1805015 | Invader | CGCGCCGAGGAGTTGCTGAAGCTGC | ATGACGTGGCAGACGGTTGCTGAAGCTGC |
| rs1801275 | Invader | CGCGCCGAGGAGGAGTTTGTACATGCG | ATGACGTGGCAGACGGGAGTTTGTACATGCG |
| rs1805014 | Invader | CGCGCCGAGGTCAGAGAAGAGTAAATCCTCA | ATGACGTGGCAGACCCAGAGAAGAGTAAATCCTC |
| IL4: | |||
| rs2069757 | TaqMan | TTTAAGGCTGGAAGGATA | TTTAAGGCTGAAAGGATA |
| rs1295683 | TaqMan | ACAGAACCAAGCTGC | ACAGAACCGAGCTGC |
| rs2243302 | TaqMan | CCAGATGGGCCCTC | CAGACGGGCCCTC |
| rs2243238 | Invader | NA | NA |
| rs2243307 | Invader | NA | NA |
| rs2243248 | TaqMan | TGGTAAGACGGTAGCTC | TTGGTAAGACTGTAGCTC |
| rs2243250 | TaqMan | CATTGTCCCCCAGTGCT | CATTGTTCCCCAGTGCT |
| rs2227282 | TaqMan | CAGAGCAACTAAAAC | CAGAGCAAGTAAAAC |
| rs2243267 | TaqMan | TTACAGAAGCAAAAAT | TTACAGAACCAAAAAT |
| rs2243268 | TaqMan | CTCAATCCCATGTTCTC | CAATCCCCTGTTCTC |
| rs2243281 | TaqMan | CCACCATCGTCTCTAG | CCACCATCATCTCTAG |
| rs2243291 | TaqMan | CCACTGTGCACAGTGT | CCACTGTGGACAGTGT |
| IL13: | |||
| rs848 | TaqMan | CAGTGGACACCAGGAG | CAGTGGACCCCAGGAG |
| rs1295683 | TaqMan | ACAGAACCAAGCTGC | ACAGAACCGAGCTGC |
| rs2066960 | TaqMan | CACCATAATAGGCCC | ACCATCATAGGCCC |
| rs1295686 | TaqMan | AGGTCAGCACGTGAGTA | AGGTCAGCACATGAGTA |
| rs1800925 | TaqMan | CTTCCCTCGTTTTCCT | TTCCCTCATTTTCCT |
| rs1881457 | TaqMan | CGTGTGACCCCTCTAC | CGTGTGACCCCGCTAC |
| rs1520541 | TaqMan | AGGGACGGTTCAAC | AGGGACAGTTCAAC |
Note.— NA = sequence not available.