Table A4.
Estimated IL4 and IL13 Haplotype Frequencies in Controls and Patients with T1D[Note]
| Haplotypea | MAF in Controls/MAF in Patients with T1D | OR | 95% CI |
| 11111 | .8643/.8621 | Reference | … |
| 22221 | .0304/.0279 | .94 | .76–1.16 |
| 22111 | .0234/.0252 | 1.12 | .90–1.39 |
| 11112 | .0255/.0239 | 1.10 | .87–1.39 |
| 22222 | .0199/.0202 | 1.13 | .88–1.45 |
| 11221 | .0190/.0221 | 1.19 | .93–1.50 |
Note.— Data are for IL13 −1512A→C (rs1881457), IL13 −1112C→T (rs1800925), IL13 +1923C→T (rs1295686), IL13 R110Q (rs20541), and IL4 −524C→T (rs2243250). To correct for regional variation in allele frequencies, the analyses were stratified according to 12 broad geographical regions within Great Britain (D.G.C., unpublished data).
a
The five most common haplotypes (with MAF >0.01) are shown. “1” denotes the presence of the reference allele, and “2” denotes the presence of the variant allele for each SNP.