Figure 1.

Simplified pedigree of the Finnish family with PSP. HRCT (indicated by an asterisk [*]) was performed for all living family members except individual 25. Affected members (blackened symbols) have ⩾1 bullae on their lungs, detected by HRCT or during surgery (individual 25). Arrows indicate those who had experienced a PSP episode, and numbers indicate those from whom DNA samples were obtained. The presence of bullae could not be confirmed for two individuals who died prior to the study; hence, they were classified as unaffected, even though both had experienced PSP.