Table 1.
Sample Overview
|
No. of Families |
No. of Samples |
||||
| Sample andLocation | Multicase | Single Case | Affecteda | Unaffected | Total |
| Family: | |||||
| Uppsala, Sweden | 3 | 38 | 45 | 66 | 111 |
| Lund, Sweden | 3 | 128 | 146 | 376 | 522 |
| Finland | 37 | 72 | 150 | 237 | 387 |
| Iceland | 11 | … | 30 | 119 | 149 |
| Unrelated: | |||||
| Uppsala, Sweden | … | … | 33 | 256 | 289 |
| Lund, Sweden | … | … | 15 | … | 15 |
| Umeå, Sweden | … | … | 260 | … | 260 |
| Finland | … |
… |
… |
182 |
182 |
| Total | 54 | 238 | 679 | 1,236 | 1,915 |
a
There were 88%, 92%, and 88% females among the Swedish, Finnish, and Icelandic patients, respectively. The age (± SD) at SLE diagnosis was 37.4±15.5 years in Sweden, 31.8±12.5 years in Finland, and 29.9±12.4 in Iceland (P=.001). The mean number of ACR criteria observed in the patients was 5.6±1.6 in Sweden and 5.4±1.3 in Finland. Information on ACR criteria was not available for the Icelandic patients.