Table 1.
Results of ASHBD Association Test with Serotonin Level[Note]
|
P Valuea for |
||||||
| Chromosomeand Locus | Distance from p-ter(cM) | AssociatedAllele | Frequency | All Samples | Males | Females |
| 1: | ||||||
| D1S1589 | 192 | 205 | .48 | .0232 | .0006 | >.1 |
| 2: | ||||||
| D2S125 | 261 | 94 | .20 | .0028 | .0003 | >.1 |
| 10: | ||||||
| D10S1677 | 100 | 174 | .32 | .0504 | >.1 | .0005 |
| 17: | ||||||
| ATA58E08 | 47 | 111 | .23 | .0289 | .0004 | >.1 |
| D17S1294 | 51 | 260 | .22 | .0106 | .0002 | >.1 |
| 5HTT_SNP09b | 51 | A | .57 | .0191 | .0003 | >.1 |
| D17S1299 | 62 | 196 | .55 | .0005 | .0001 | >.1 |
| ITGB3_33 | 66 | L | .80 | .0002 | .0003 | .0751 |
Note.— All ASHBD results with P values reaching the threshold for suggestive significance (see “Material and Methods” section) in one of the three samples are shown. All loci included here showed association with decreased serotonin levels.
a
P values are Bonferroni corrected (see “Material and Methods” section for details). Results in bold italics met criteria for suggestive significance.
b
dbSNP accession number rs2066713.