Table 2.
Findings for CAG-Repeat Length |
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Continuous |
<22 versus ⩾22 |
<23 versus ⩾23 |
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Subjects | No. of Controls/Cases | ORa | 95% CI | Pb | ORa | 95% CI | Pb | ORa | 95% CI | Pb |
All cases | 2,160/2,036 | 1.016 | .997–1.036 | .11 | 1.084 | .954–1.231 | .22 | 1.115 | .981–1.267 | .09 |
Advanced cases | 2,160/686 | 1.015 | .988–1.044 | .28 | 1.094 | .913–1.310 | .33 | 1.122 | .936–1.345 | .21 |
Local cases | 2,160/1,239 | 1.013 | .991–1.036 | .25 | 1.068 | .922–1.238 | .38 | 1.087 | .937–1.261 | .27 |
Note.— There is no statistically significant association between the CAG-microsatellite polymorphism and prostate cancer risk for the entire population or when stratified by stage. Multiple analyses were performed, by using two cut points (22 and 23) as well as by modeling the CAG-repeat length as a continuous variable. These analyses demonstrate no significant association between prostate cancer risk and CAG-repeat length.
Adjusted for race/ethnicity and age.
Two-sided P value.