Table 3.
Findings for the Minor Allele of Each AR SNP and Risk of Prostate Cancer |
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All Cases |
Advanced-Stage Cases |
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SNP | ORa | 95% CI | Pb | ORa | 95% CI | Pb |
rs6525177 | .93 | .61–1.42 | .75 | .89 | .50–1.57 | .69 |
rs12557549 | 2.32 | .44–12.31 | .32 | 2.49 | .33–19.03 | .38 |
rs5964602 | .90 | .60–1.36 | .61 | .85 | .49–1.48 | .56 |
rs962458 | 1.22 | .79–1.89 | .36 | 1.40 | .80–2.46 | .24 |
rs12007229 | .75 | .48–1.18 | .21 | .51 | .26–1.01 | .05 |
rs6152 | 1.15 | .79–1.66 | .47 | 1.24 | .77–2.0 | .37 |
rs1204041 | .61 | .36–1.03 | .07 | .42 | .20–.90 | .02 |
rs1204040 | 1.20 | .80–1.79 | .37 | 1.09 | .64–1.86 | .76 |
rs1204038 | .88 | .59–1.33 | .55 | .85 | .49–1.46 | .56 |
rs2361630 | 1.17 | .81–1.71 | .41 | 1.29 | .79–2.12 | .31 |
rs1926925 | .58 | .33–1.02 | .06 | .35 | .15–.86 | .02 |
rs1926926 | .55 | .32–.96 | .04 | .29 | .11–.72 | .01 |
rs1926927 | .54 | .31–.95 | .03 | .33 | .14–.81 | .01 |
rs2361634 | .62 | .26–1.48 | .28 | 1.09 | .39–3.0 | .88 |
rs2361636 | .46 | .25–.86 | .01 | .28 | .10–.75 | .01 |
rs1361039 | 1.35 | .29–6.39 | .70 | 2.26 | .35–14.48 | .39 |
rs1337077 | .63 | .36–1.10 | .11 | .41 | .18–.96 | .04 |
rs1337078 | .58 | .33–1.02 | .06 | .40 | .17–.92 | .03 |
rs1337079 | .57 | .32–.99 | .05 | .34 | .14–.81 | .02 |
rs1337080 | .99 | .62–1.57 | .96 | .83 | .45–1.55 | .56 |
rs1572500 | .54 | .30–.97 | .04 | .39 | .16–.96 | .04 |
ARa15 | 4.63 | .47–45.9 | .19 | 6.18 | .52–74.03 | .15 |
rs1337075 | .56 | .31–1.02 | .06 | .34 | .13–.86 | .02 |
rs1572501 | 3.19 | .66–15.42 | .15 | .87 | .08–10.13 | .91 |
rs1361038 | 1.12 | .57–2.19 | .75 | .85 | .34–2.11 | .73 |
rs1337076 | 1.07 | .63–1.82 | .81 | .88 | .44–1.78 | .73 |
rs10060 | 1.01 | .63–1.63 | .97 | .96 | .52–1.78 | .89 |
rs1337082 | .96 | .65–1.41 | .84 | .90 | .54–1.49 | .68 |
rs945052 | .98 | .59–1.61 | .93 | .85 | .44–1.64 | .62 |
rs945048 | .94 | .57–1.54 | .80 | .77 | .39–1.50 | .43 |
rs945050 | .87 | .61–1.25 | .45 | .81 | .51–1.31 | .40 |
rs1361037 | 1.10 | .67–1.83 | .71 | .89 | .45–1.76 | .74 |
Note.— All 32 SNPs across the AR are individually tested for association with prostate cancer in the entire MEC population.
Adjusted for age and race/ethnicity.
P values are two-sided, with no correction for multiple testing.