Table 4.
Association of AR Haplotypes with Risk of Prostate Cancer[Note]
|
Frequency (%) among |
|||||
| LD Block (No. of Cases/Controls) and Haplotype | Cases | Controls | OR | 95% CI | P |
| 1 (843/805): | |||||
| GCCGCAGAATACAAGGGAAAGCCTA | 12.3 | 12.1 | 1.05 | .77–1.44 | .76 |
| GCCGCAGAATACAAGGGAAGGCCTA | 9.6 | 10.1 | .96 | .68–1.34 | .79 |
| GCCGCAAAATACAAGGGAAGGCCTG | 5.7 | 6.3 | .89 | .59–1.36 | .59 |
| GCCGCAAAATACAAGGGAAGGCCCG | 4.0 | 2.5 | 1.73 | .98–3.06 | .06 |
| GCCAAAGAATACAAGGGAAAGCCTA | 3.0 | 2.5 | 1.25 | .65–2.40 | .51 |
| GCCAAGACACTTGAAGAGGATCTTA | 9.4 | 12.2 | .75 | .54–1.04 | .09 |
| ACAACGGCGCACAAGGGAAAGCCTA | 49.4 | 47.1 | 1.12 | .85–1.48 | .43 |
| ACAACGGCGCACAGGGGAAAGCCTA | 1.2 | 1.5 | .73 | .29–1.81 | .49 |
| 2 (876/863): | |||||
| GAGCACA | 21.7 | 24.3 | .88 | .70–1.12 | .30 |
| GAACATA | 49.6 | 46.7 | 1.09 | .83–1.42 | .53 |
| GGGTTTG | 10.2 | 9.7 | 1.15 | .80–1.65 | .46 |
| TGGTTTG | 16.7 | 16.4 | 1.09 | .81–1.46 | .56 |
Note.— Haplotypes are compared against all other haplotypes (see the “Materials and Methods” section). No associations between common haplotype and prostate cancer are observed.