TABLE 1.
Patient characteristics.
| Characteristics | CHD patients (n = 16) | Healthy donors (n = 16) | p value for trend |
|---|---|---|---|
| Age, yrs | 59.88 ± 10.77 | 53.44 ± 6.89 | 0.055 |
| Female, n (%) | 8 (50%) | 9 (56.25%) | 1.00 |
| Body mass index, kg/m2 | 24.55 ± 1.80 | 24.37 ± 3.14 | 0.846 |
| Blood pressure, mmHg | |||
| Systolic | 122.88 ± 8.43 | 126.38 ± 8.37 | 0.248 |
| Diastolic | 70.00 ± 6.78 | 81.94 ± 7.51 | 0.000 |
| Comorbidity, n (%) | |||
| Prior MI | 4 (25%) | 0 | |
| Prior PCI | 3 (18.75%) | 0 | |
| Prior CABG | 1 (6.25%) | 0 | |
| Prior stroke | 1 (6.25%) | 0 | |
| Hypertension | 6 (37.5%) | 0 | |
| Diabetes mellitus | 2 (12.5%) | 0 | |
| Hyperlipoidemia | 5 (31.25%) | 0 | |
| Current smoker | 2 (12.5%) | 3 (18.75%) | |
| Drinking history | 7 (43.75%) | 5 (31.25%) | |
| Previous antiplatelet medication, n (%) | |||
| Aspirin | 7 (43.75%) | 0 | |
| Clopidogrel | 2 (12.5%) | 0 | |
| Current Medication,n (%) | |||
| Beta-blocker | 2 (12.5%) | 0 | |
| Nitrates | 2 (12.5%) | 0 | |
| Statins | 12 (75%) | 0 | |
| Calcium-channel blocker | 5 (31.25%) | 0 | |
| ACEI | 1 (6.25%) | 0 | |
| ARB | 1 (6.25%) | 0 | |
| Hypoglycemic drugs | 2 (12.5%) | 0 | |
| Trimetazidine | 1 (6.25%) | 0 | |
| Laboratory data | |||
| WBC, 109/L | 6.33 ± 1.34 | 8.35 ± 11.90 | 0.506 |
| RBC, 1012/L | 4.61 ± 0.40 | 4.67 ± 0.40 | 0.724 |
| HGB, g/L | 141.50 ± 13.13 | 142.13 ± 11.54 | 0.887 |
| PLT, 109/L | 259.25 ± 51.14 | 226.44 ± 42.53 | 0.058 |
| PCT, % | 0.26 ± 0.05 | 0.24 ± 0.04 | 0.173 |
| PDW, fL | 10.96 ± 1.11 | 12.26 ± 2.62 | 0.084 |
| MPV, fL | 10.03 ± 0.52 | 10.50 ± 1.09 | 0.136 |
| P-LCR, % | 24.70 ± 4.43 | 28.52 ± 8.46 | 0.120 |
| TG, mmol/L | 1.38 ± 0.93 | 1.07 ± 0.32 | 0.22 |
| TC, mmol/L | 4.45 ± 0.97 | 4.48 ± 0.77 | 0.921 |
| HDL-C, mmol/L | 1.23 ± 0.29 | 1.23 ± 0.25 | 0.979 |
| LDL-C, mmol/L | 2.45 ± 0.70 | 2.73 ± 0.50 | 0.208 |
| BUN, mmol/L | 14.95 ± 7.26 | 13.52 ± 2.59 | 0.465 |
| CR, mmol/L | 73.38 ± 20.81 | 67.93 ± 10.90 | 0.361 |
| UA,mmol/L | 357.38 ± 116.38 | 252.64 ± 53.86 | 0.003 |
| PT, sec | 10.84 ± 0.49 | 10.91 ± 0.41 | 0.669 |
| PTA, % | 110.81 ± 6.58 | 113.97 ± 17.65 | 0.508 |
| INR | 0.94 ± 0.04 | 0.94 ± 0.04 | 0.786 |
| APTT, sec | 26.77 ± 1.76 | 28.18 ± 1.61 | 0.025 |
| TT, sec | 17.05 ± 0.61 | 17.41 ± 0.33 | 0.047 |
| Fbg, g/L | 3.13 ± 0.72 | 2.61 ± 0.39 | 0.020 |
| Echocardiography | |||
| LAD, mm | 36.44 ± 3.97 | 33.06 ± 2.57 | 0.008 |
| IVST, mm | 8.56 ± 0.63 | 8.25 ± 0.86 | 0.249 |
| LVD, mm | 49.00 ± 4.62 | 46.06 ± 3.11 | 0.043 |
| LVPWT, mm | 8.50 ± 0.52 | 8.25 ± 0.86 | 0.325 |
| RVPWT, mm | 4 | 4 | |
| LVEF, % | 62.13 ± 4.56 | 67.06 ± 3.92 | 0.003 |