Table 1. Patient characteristics.

Variables	Patients(n=41)
Age at onset, years, mean (SD)	66.9 (12.7)
Men, n (%)	20 (49)
Bulbar onset, n (%)	7 (17)
Age at diagnosis, years, mean (SD)	68.3 (12.5)
Duration from symptom onset to diagnosis, months, mean (SD)	16.6 (12.3)
Revised El Escorial criteria at diagnosis, definite or probable, n (%)	25 (61)
%FVC at diagnosis, %, mean (SD)	74.8 (29.2)
ALSFRS-R at diagnosis, mean (SD)	35.3 (8.2)
BMI, kg/m2, mean (SD)	20.6 (3.6)
sNfL, pg/mL, median (IQR)	113(72.9–155)*
cNfL, pg/mL, median (IQR)	7503(3981–10,949)†

^*Calculated for 42 samples. Calculated for .

^†Calculated for 36 samples.

ALSFRS-RAmyotrophic Lateral Sclerosis Functional Rating Scale RevisedBMIbody mass indexcNfLcerebrospinal fluid neurofilament light chain%FVCpercentage of predicted forced vital capacitysNfLserum neurofilament light chain