Table 2. Stroke characteristics and atherosclerosis scores of the enrolled patients.
| Variables |
Total (N = 4,699 [100%]) |
CHIP carriers (N = 180 [3.8%]) |
Non-CHIP carriers (N = 4,519 [96.2%]) |
P Value |
|---|---|---|---|---|
| TOAST classification, n. (%) | 0.33 | |||
| LAA | 1652 (35.2) | 58 (32.2) | 1594 (35.3) | |
| CE | 256 (5.4) | 12 (6.7) | 244 (5.4) | |
| SAO | 954 (20.3) | 29 (16.1) | 925 (20.5) | |
| SOE | 66 (1.4) | 2 (1.1) | 64 (1.4) | |
| SUE | 1771 (37.7) | 79 (43.9) | 1692 (37.4) | |
| Admitting NIHSS, n | 0.51 | |||
| Mean±SD | 4.5±4.3 | 4.7±4.3 | 4.5±4.3 | |
| Admitting NIHSS, n. (%) | 0.90 | |||
| ≤ 3 | 2327 (49.5) | 90 (50.0) | 2237 (49.5) | |
| ＞3 | 2372 (50.5) | 90 (50.0) | 2282 (50.5) | |
| ICAS | 0.99 | |||
| 0 | 2060 (43.8) | 79 (43.9) | 1981 (43.8) | |
| ＞0 | 2639 (56.2) | 101 (56.1) | 2538 (56.2) | |
| AS | 0.96 | |||
| Mean±SD | 1.6±1.9 | 1.6±1.8 | 1.6±1.9 |
TOAST, Trial Org 10,172 in Acute Stroke Treatment; LAA, Large-artery atherosclerosis; CE, Cardiac embolism; SAO, Small-artery occlusion; SOE, stroke of other determined etiology; SUE, stroke of undetermined etiology; NIHSS, National Institutes of Health Stroke Scale. “ICAS = 0” indicating no stenosis, “ICAS ＞0” indicating 0-99% stenosis or occlusion. Atherosclerosis Scores (AS) were used to evaluate the atherosclerosis burden, which was determined by the number and degree of steno-occlusion of the intracranial arteries.