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. 2025 Mar 28;9:e2400815. doi: 10.1200/PO-24-00815

TABLE 2.

Biomarker Testing Type and Results in the Full EHR Data Set

Biomarker Full EHR Data Set (N = 2,982)a
HER2, No. (%) 612 (21)
 Equivocal 66 (11)
 Negative 449 (73)
 Positive 75 (12)
 Unknownb 22 (4)
MMR/MSI, No. (%) 1,604 (54)
 Equivocal NRc
 Loss of MMR protein expression (MMR protein deficiency) 369 (23)
 MSI-ambiguous NRc
 MSI-high 38 (2)
 MSI-low NRc
 MSS 211 (13)
 Normal MMR protein expression 902 (56)
 Unknownb 77 (5)
ER/PR, No. (%) 1,465 (49)
 Indeterminate result NRc
 Negative 288 (20)
 Positive 1,129 (77)
 Unknown 47 (3)

Abbreviations: EHR, electronic health record; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; MMR, DNA mismatch repair; MSI, microsatellite instability; MSS, microsatellite stable; NR, not reported; PR, progesterone receptor.

a

Percentages are testing rates among all patients and result rates among patients who received testing.

b

Included pending, unknown, and unsuccessful/indeterminate tests.

c

The number of patients was not reported because of a sample size of ≤5.