Table 2.
Comparisons of demographic, PSG characteristics and the urinary 8-OHdG concentration among the primary snoring, the OSA without cognitive impairment and the OSA with cognitive impairment groups.
| Characteristics | Primary Snoring (n = 35) | OSA without CI (n = 43) | OSA with CI (n = 53) | p |
|---|---|---|---|---|
| Males (%) | 57.1 | 62.8 | 60.4 | 0.879 |
| Age (years) | 7.93 ± 1.99 | 8.41 ± 2.45 | 7.5 (6, 9) | 0.413 |
| BMI (kg/m2) | 16 (15.38, 20.2) | 17.5 (15.5, 20) | 17.3 (15.33, 22.6) | 0.419 |
| NREM1 (%) | 5.03 ± 3.07 | 3.8 (1.6, 7.3) | 4 (1.3, 9.65) | 0.702 |
| NREM2 (%) | 52.39 ± 5.97 | 50.55 ± 7.38 | 49.02 ± 8.45 | 0.123 |
| NREM3 (%) | 23.4 (19.7, 25.2) | 25.79 ± 6.36 | 26.78 ± 7.02 | 0.046 |
| REM (%) | 18.72 ± 4.91 | 18.83 ± 5.11 | 18.69 ± 4.73 | 0.99 |
| Minimum SaO2 (%) | 91 (89, 94) | 90 (88, 92) | 88 (84.5, 92) | 0.001 |
| Average SaO2 (%) | 97 (97, 97) | 97 (96, 97) | 97 (96, 97) | 0.022 |
| OAHI | 0.4 (0.3, 0.7) | 2.4 (1.7, 5.3) | 4.2 (2.3, 10.45) | <0.001 |
| ODI | 0.5 (0.1, 1.1) | 1.8 (0.5, 3.4) | 1.7 (0.8, 7.25) | <0.001 |
| 8-OHdG (pg/mL) | 230.72 ± 13.82 | 244.55 (227.15, 258.55) | 253.23 ± 13.69 | <0.001 |
PSG, polysomnography; OSA, obstructive sleep apnea; CI, cognitive impairment; BMI, body mass index; SaO2, arterial oxygen saturation; OAHI, obstructive apnea-hypopnea index; ODI, oxygen desaturation index.