Table 3.
Performance of the Acute Pulmonary Embolism Detection Algorithm Across Age and Sex Subgroups
| Group | N | AUROC | Sensitivity (95% CI) (%) | Specificity (95% CI) (%) | OR (95% CI) | |
|---|---|---|---|---|---|---|
| Age <50 y | 4159 | 0.672 (0.638-0.705) | 55.4 (49.1-61.5) | 69.2 (67.8-70.7) |  |
2.8 (2.2-3.6) |
| Age ≥50 y | 11,901 | 0.693 (0.677-0.709) | 65.3 (62.5-67.9) | 63.0 (62.1-63.9) | 3.2 (2.8-3.6) | |
| Female | 8296 | 0.684 (0.663-0.705) | 55.3 (51.5-59.1) | 70.3 (69.2-71.3) | 2.9 (2.5-3.4) | |
| Female <50 y | 2409 | 0.652 (0.607-0.697) | 41.1 (32.5-50.1) | 74.7 (72.9-76.5) | 2.1 (1.4-3.0) | |
| Female ≥50 y | 5887 | 0.687 (0.663-0.711) | 58.7 (54.4-62.9) | 68.4 (67.1-69.6) | 3.1 (2.6-3.7) | |
| Male | 7764 | 0.696 (0.676-0.716) | 70.2 (66.9-73.3) | 58.5 (57.3-59.6) | 3.3 (2.8-3.9) | |
| Male <50 y | 1750 | 0.692 (0.642-0.742) | 69.5 (60.8-77.2) | 61.5 (59.1-63.9) | 3.6 (2.5-5.3) | |
| Male ≥50 y | 6014 | 0.695 (0.673-0.716) | 70.3 (66.8-73.7) | 57.6 (56.2-58.9) | 3.2 (2.7-3.8) | |
| Overall | 16,060 | 0.693 (0.673-0.716) | 63.5 (61.0-66.0) | 64.7 (63.9-65.4) | 3.2 (2.9-3.6) | |
| OR |
Abbreviations: AUROC, area under the receiver operating characteristic curve; OR, odds ratio.