Skip to main content
. 2025 Mar 21;82:103153. doi: 10.1016/j.eclinm.2025.103153

Table 2.

Mean and Standard Deviation of baseline HRQoL scale scores of the whole patient population and by patient characteristics at baseline (N = 16,210).

HRQoL Scale Overall
Age Group
Sex
WHO Performance Statusa
Metastasis Status
All ≤ 60 >60 Male Female Active Restricted Metastatic Non-metastatic
All observations 16,210 9130 7080 6647 9563 7211 7558 5709 8837
Physical functioning 80 (21) 83 (20) 76 (22) 79 (22) 80 (21) 88 (16)b 70 (23) 75 (22) 84 (19)
Role functioning 71 (32) 72 (31) 70 (32) 71 (32) 72 (31) 81 (26)b 59 (33) 67 (32) 76 (30)
Emotional functioning 73 (22) 71 (22) 75 (22) 76 (22) 70 (23) 76 (21) 70 (23) 73 (22) 73 (22)
Cognitive functioning 84 (21) 84 (20) 83 (21) 85 (20) 83 (21) 87 (18) 80 (22) 85 (20) 85 (20)
Social functioning 76 (28) 76 (28) 76 (28) 76 (27) 75 (28) 82 (24)b 66 (30) 72 (29) 79 (26)
Global health status/QoL 65 (23) 67 (23) 62 (23) 63 (23) 66 (23) 73 (20)b 55 (23) 60 (23) 69 (22)
Fatigue 33 (26) 32 (26) 35 (26) 33 (26) 33 (26) 24 (22)b 44 (26) 38 (26)b 28 (25)
Nausea/vomiting 15 (20) 14 (19) 17 (20) 14 (19) 16 (20) 9 (15)b 23 (22) 19 (20) 11 (18)
Pain 26 (28) 26 (28) 25 (28) 26 (29) 25 (28) 18 (23)b 35 (31) 31 (29)b 20 (25)
Dyspnoea 18 (26) 16 (25) 21 (27) 21 (27) 16 (25) 11 (21)b 26 (29) 25 (28)b 13 (23)
Insomnia 30 (31) 31 (31) 27 (30) 27 (30) 32 (31) 26 (29) 34 (32) 31 (31) 28 (30)
Appetite loss 20 (29) 18 (28) 22 (31) 20 (29) 20 (29) 12 (23)b 29 (33) 26 (31)b 15 (26)
Constipation 15 (26) 14 (25) 18 (28) 15 (26) 16 (27) 11 (22)b 21 (30) 19 (28) 12 (24)
Diarrhoea 8 (18) 8 (18) 8 (19) 8 (18) 8 (19) 7 (17) 9 (20) 9 (19) 7 (17)
Financial problems 17 (28) 21 (31)b 11 (23) 18 (29) 16 (28) 15 (26) 21 (30) 19 (29) 15 (27)
a

Active WHO Performance Status (PS = 0); Restricted WHO Performance Status (PS = 1 to 4).

b

Differences that are clinically meaningful based on a 10-pt. threshold.