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. 2025 Mar 21;82:103153. doi: 10.1016/j.eclinm.2025.103153

Table 3.

Mean and Standard Deviation of baseline HRQoL scale scores of the whole patient population and by disease site at baseline (N = 16,210).

HRQoL Scale Overall Anal Bladder Brain Breast Colorectal Endometrial Gastric Head and Neck Lung
All observations 16,210 60 228 822 3466 1693 92 324 330 2732
Physical functioning 80 (21) 82 (20) 70 (26) 79 (23) 90 (15) 79 (19) 75 (23) 87 (16) 87 (17) 72 (21)
Role functioning 71 (32) 74 (29) 57 (37) 65 (33) 85 (24) 74 (28) 64 (33) 77 (28) 82 (26) 67 (31)
Emotional functioning 73 (22) 63 (24) 65 (27) 73 (23) 70 (21) 79 (19) 68 (24) 72 (23) 73 (23) 74 (23)
Cognitive functioning 84 (21) 78 (25) 80 (25) 70 (27) 85 (19) 87 (17) 83 (21) 85 (20) 89 (17) 84 (20)
Social functioning 76 (28) 78 (26) 69 (33) 68 (30) 84 (23) 74 (27) 76 (28) 77 (28) 86 (21) 73 (27)
Global health status/QoL 65 (23) 63 (23) 50 (25) 64 (23) 74 (21) 63 (22) 64 (23) 66 (23) 62 (22) 60 (22)
Fatigue 33 (26) 33 (26) 46 (31) 35 (25) 23 (21) 35 (24) 35 (27) 33 (27) 26 (25) 39 (25)
Nausea/vomiting 15 (20) 5 (14) 12 (22) 14 (18) 10 (16) 19 (18) 10 (18) 11 (19) 4 (13) 22 (20)
Pain 26 (28) 33 (32) 41 (36) 13 (21) 18 (23) 27 (27) 30 (30) 27 (27) 28 (25) 27 (28)
Dyspnoea 18 (26) 12 (24) 19 (27) 11 (21) 9 (19) 21 (25) 14 (26) 15 (24) 13 (22) 32 (30)
Insomnia 30 (31) 39 (33) 39 (37) 26 (32) 31 (29) 26 (28) 35 (32) 28 (30) 27 (30) 27 (30)
Appetite loss 20 (29) 18 (26) 36 (38) 10 (22) 11 (21) 25 (29) 28 (30) 19 (28) 22 (30) 25 (31)
Constipation 15 (26) 23 (33) 35 (36) 13 (25) 9 (19) 15 (25) 24 (33) 15 (25) 15 (26) 17 (27)
Diarrhoea 8 (18) 8 (15) 8 (20) 5 (15) 6 (15) 11 (21) 9 (20) 18 (28) 4 (13) 6 (16)
Financial problems 17 (28) 15 (24) 13 (26) 14 (27) 15 (27) 17 (27) 14 (26) 18 (29) 18 (28) 22 (31)
HRQoL scale Lymphoma Melanoma Mixed population Multiple myeloma Ovarian Pancreatic Prostate Soft tissue sarcoma Testicular
All observations 348 861 811 318 2269 516 645 425 270
Physical functioning 78 (21) 92 (12) 60 (27) 78 (17) 75 (22) 75 (21) 90 (14) 77 (22) 82 (23)
Role functioning 57 (34) 84 (24) 50 (34) 69 (29) 59 (35) 61 (33) 91 (19) 71 (31) 57 (35)
Emotional functioning 67 (24) 82 (18) 68 (23) 82 (18) 69 (24) 67 (24) 83 (17) 74 (23) 67 (24)
Cognitive functioning 84 (21) 93 (14) 76 (24) 86 (17) 81 (22) 81 (22) 87 (16) 85 (20) 87 (19)
Social functioning 72 (30) 88 (20) 64 (31) 70 (27) 67 (31) 66 (30) 93 (15) 75 (28) 68 (31)
Global health status/QoL 55 (22) 78 (18) 53 (24) 67 (19) 59 (23) 54 (23) 77 (18) 64 (23) 58 (23)
Fatigue 49 (26) 15 (18) 47 (28) 33 (21) 41 (26) 45 (27) 15 (18) 33 (25) 40 (28)
Nausea/vomiting 10 (18) 1 (6) 34 (23) 22 (18) 17 (23) 21 (21) 2 (7) 7 (15) 12 (19)
Pain 34 (32) 12 (20) 56 (32) 30 (26) 30 (28) 38 (30) 10 (18) 29 (30) 44 (34)
Dyspnoea 30 (30) 5 (14) 25 (30) 14 (21) 19 (27) 17 (25) 12 (21) 20 (27) 17 (27)
Insomnia 49 (36) 18 (26) 39 (33) 25 (28) 35 (32) 34 (31) 16 (23) 26 (29) 38 (35)
Appetite loss 29 (33) 3 (12) 27 (33) 14 (24) 25 (33) 42 (35) 3 (11) 17 (27) 33 (33)
Constipation 16 (27) 5 (13) 24 (32) 7 (18) 23 (31) 27 (33) 7 (18) 15 (26) 17 (28)
Diarrhoea 9 (20) 6 (15) 8 (20) 7 (16) 10 (21) 15 (26) 6 (15) 7 (17) 8 (18)
Financial problems 23 (33) 14 (26) 20 (30) 23 (30) 14 (26) 21 (30) 3 (11) 19 (29) 23 (32)