Table 3–

Patient-reported outcomes by randomization arm where differences are calculated as the difference in the transrectal arm subtracted from the transperineal arm adjusted for study site

Characteristic	N	Transperineal (N = 287)	Transrectal (N = 280)	Adjusted difference	95% Confidence interval
Biopsy pain	548	3.6 (2.3)	3.0 (2.1)	0.6	0.2, 0.9
Unknown		10	9
Biopsy pain ≥7 (severe)	548	33 (12%)	19 (7.0%)	5.0%	−0.1%, 10%
Unknown		10	9
Biopsy discomfort	554	4.2 (2.5)	3.8 (2.3)	0.4	0.0, 0.8
Unknown		9	4
Biopsy anxiety	565	3.9 (3.0)	4.2 (2.9)	−0.3	−0.8, 0.1
Unknown		1	1
7-d survey discomfort	448	2.1 (2.4)	1.7 (2.2)	0.3	–0.1, 0.7
Unknown		61	58
7-d survey pain present	449	22 (9.7%)	32 (14%)	−5.2%	−12%, 1.5%
Unknown		61	57
7-d survey pain score >3	444	15 (6.6%)	13 (6.0%)	0.8%	−4.6%, 6.3%
Unknown		61	62

ANCOVA = analysis of covariance.

For continuous variables, values are presented as mean (standard deviation); ANCOVA was used to generate the differences adjusted for site. For categorical variables, values are presented as n (%); differences were adjusted for site along with 95% confidence intervals calculated using the logistic regression least-squares adjusted mean difference.