Table 2.

Weighted and unweighted PAF for ten domains

	Model 1			Model 2
Domains	Un weighted PAF	Communality	Weighted PAF	Un weighted PAF	Communality	Weighted PAF
Biochemical measurements	0.115	0.344	0.045	0.117	0.537	0.045
Circadian	0.248	0.130	0.098	0.250	0.105	0.097
Dietary	0.169	0.240	0.067	0.184	0.235	0.071
Family factors	0.082	0.172	0.032	0.082	0.042	0.032
Health and medical history	0.301	0.245	0.119	0.301	0.246	0.117
Lifestyle	0.252	0.184	0.099	0.265	0.145	0.103
Physical activity	0.257	0.212	0.101	0.263	0.198	0.102
Physical measures	0.247	0.118	0.097	0.256	0.205	0.100
Psychosocial factors	0.264	0.236	0.104	0.288	0.184	0.112
Sociodemographics	0.246	0.119	0.097	0.222	0.103	0.087
Overall weighted PAF			85.9			86.6

The calculation of the weighted PAF considered the overlap between risk factors. The unfavorable profiles were reclassified as intermediate or favorable categories in model 1. In model 2, all risk factors were reclassified into the favorable tertile. Robust and pre-frailty individuals were set as the control group

PAF population attributable fraction