Table 1.

Details of the disomic control and trisomic DS iPSC lines.

Cell label	Cell line	Donor origin	Reprogramming method	Provider
C2	WC-24-02-DS-A	Mosaic DS individual Female Aged 25 Skin fibroblast	Non-integrating episomal vector	WiCell Research Institute, University of Wisconsin
DS2	WC-24-02-DS-M
C4	ATCC-DYS0100	Healthy individual Male Neonate Skin fibroblast	Sendai viral transfection system	American Type Culture Collection (ATCC)
DS3	UWWC1-2DS3	Trisomy 21 individual Male Neonate Skin fibroblast	Non-integrating episomal vector	WiCell Research Institute, University of Wisconsin
C5	HPS4272	Trisomy 21 individual Male Aged <10 Skin fibroblast	Non-integrating episomal vector	RIKEN BioResource Center, Japan
DS4	HPS4270