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. 2025 Mar 24;13:1545431. doi: 10.3389/fbioe.2025.1545431

TABLE 1.

Baseline characteristics of the included studies.

Author and year Study design K-L1(n) K-L2(n) K-L3 (n) K-L4(n) Hips Follow-up (months) Molecular weight (HA)kDa Group Sample size Age (years) Female
Dallari et al. (2016) RCT 22 18 24 16 80 12 1,500–3,200 PRP + HA 31 MD 19
PRP 44 24
Nouri et al. (2022) RCT 0 33 30 0 63 6 2,500–3,200 PRP + HA 31 60.29 23
PRP 32 58.22 22
Palco et al. (2021) Cohort 0 24 28 0 52 12 MD PRP + HA 26 64.81 14
PRP 26 50.62 10

Abbreviations: RCT, Randomized Clinical Trial; K-L, Kellgren-Lawrence scale; PRP, Platelet Rich Plasma; HA, Hyaluronic Acid; MD, Missing Data.