Fig. 5.

MRI for in vivo immune cell tracking. (A) Schematic representation of MRI tracking of SPIO labeled cells. Cells are labeled with SPIO nanoparticles via co-incubation, expanded and then injected intravenously. The particles can then be detected via MRI imaging.121 Copyright © 2022 The Authors. Advanced Functional Materials published by John Wiley and Sons. (B) MRI images of SPIO labeled cytotoxic cells accumulated at the tumor site and in lymph nodes in response to the combination of the DPX immunotherapy vaccine and anti-PD-1 immunotherapy.123 © 2020 The Author (s). Published with license by Taylor & Francis Group, LLC. (C) Representative MRI images of mice treated with 19F labeled splenocytes or T cells. 19F-MRI is represented in orange, which 1H-MRI is in grey.80 © 2016 Gonzales et al.