Table 2.
Sensitivity and specificity of HPV-KITE to detect all single and multiple HPVs infection positive cases (N=18, excluding cases with <50 reads mapped to any alpha HPVs) and compared with PCR-based genotyping using Luminex assay; one single HPV6 and one single HPV52 infection detected by PCR were not detected by HPV-KITE, while three PCR negative showed either HPV44 or HPV62 by HPV-KITE with at least detection coverage.
PCR | |||
---|---|---|---|
positive | negative | ||
HPV-KITE | positive | 16 | 3 |
negative | 2 | 29 | |
0.889 | 0.906 |