Table 6.
Performance of a dye combination in revealing modulated genes in B[a]P treated liver slices using an oligonucleotide array.
| B[a]P concentration dye combination |
3 μM | 10 μM | 30 μM | |||
| Cy5 – Cy3 | 36* | 11 | ||||
| Cy3 – A594 | 64 | |||||
| Cy3 – Cy5 | 47 | 13 | ||||
| A594 – Cy3 | 48 | |||||
| Cy5 – A594 | 51 | 8 | ||||
| A594 – Cy5 | 38 | |||||
* In bold the intersection of two gene lists indicating the modulated genes for a dye combination as percentage of all modulated genes (for 3, 10 and 30 μM: 121, 97 and 195 genes respectively) found by analysis of all dye combinations combined. In italics the intersection of three gene lists indicating the modulated genes for two dye combinations as percentage of all modulated genes found for all dye combinations combined. The first dye was used for B[a]P treatment, the second for the control.