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. 2025 Apr 10;24:136. doi: 10.1186/s12944-025-02541-6

Table 3.

Associations between BRI and inflammation related indicators

Model 1 Model 2 Model 3
β (95% CI) P β (95% CI) P β (95% CI) P
Neutrophil 0.15 (0.13, 0.17)  < 0.001 0.17 (0.15, 0.19)  < 0.001 0.14 (0.12, 0.16)  < 0.001
Lymphocyte 0.05 (0.04, 0.06)  < 0.001 0.05 (0.04, 0.06)  < 0.001 0.05 (0.04, 0.06)  < 0.001
Platelet 2.07 (1.32, 2.83)  < 0.001 2.10 (1.36, 2.85)  < 0.001 2.01 (1.18, 2.84)  < 0.001
Monocyte 0.01 (0.01, 0.02)  < 0.001 0.01 (0.01, 0.02)  < 0.001 0.01 (0.01, 0.02)  < 0.001
WBC 0.22 (0.20, 0.25)  < 0.001 0.24 (0.22, 0.27)  < 0.001 0.21 (0.18, 0.23)  < 0.001
SII 10.85 (7.02, 14.67)  < 0.001 11.60 (7.72, 15.48)  < 0.001 7.20 (2.79, 11.61) 0.002
NLR 0.03 (0.02, 0.04)  < 0.001 0.03 (0.02, 0.04)  < 0.001 0.01 (−0.002, 0.03) 0.091
PLR −1.94 (−2.57, −1.30)  < 0.001 −2.17 (−2.82, −1.53)  < 0.001 −2.25 (−2.91, −1.60)  < 0.001
LMR 0.01 (−0.01, 0.03) 0.443 0.004 (−0.02, 0.02) 0.716 0.01 (−0.01, 0.03) 0.228

Model 1: Adjusted for none

Model 2: Adjusted for age, gender, race/ethnicity

Model 3: Adjusted for age, gender, race/ethnicity, marital status, PIR, education level, smoking status, alcohol consumption status, physical activity, diabetes, hypertension, CKD, and CVD

Abbreviations: CI Confidence interval, WBC White blood cell, SII Systemic immune-inflammatory, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, LMR Lymphocyte-to-monocyte ratio, PIR Poverty income ratio, CKD Chronic kidney disease, CVD Cardiovascular disease