Table 1.
Parameters of the Goldbeter model (Goldbeter et al., 1990).
| Parameters of Goldbeter model | ||
|---|---|---|
| Parameter | Value | Description |
| ν0 | 1.0 μMs−1 | Constant influx of Ca2+ in to the cell |
| ν1 | 7.3 μMs−1 | InsPs-modulated release of Ca2+ from the InsP3-sensitive store |
| k | 10.0 s−1 | Constant efflux of Ca2+ in to the cell |
| kf | 1.0 s−1 | Rate constant measuring the passive, linear leak of cytosolic Ca2+into the extracellular medium |
| VM2 | 65.0 μMs−1 | Maximum values of the pumping of Ca2+ into the InsP3-insensitive store |
| VM3 | 500.0 μMs−1 | Maximum values of the release of Ca2+ into the InsP3-insensitive store |
| k2 | 1.0 μM | Threshold constants for Ca2+ pumping |
| kR | 2.0 μM | Threshold constants for Ca2+ release |
| kA | 0.9 μM | Threshold constants for Ca2+ activation |
| n | 2 | Hill coefficients characterizing these processes |
| m | 2 | Hill coefficients characterizing these processes |
| p | 4 | Hill coefficients characterizing these processes |
| β | 30.1% | External stimulation |