Table 2.
Parameters of the De Young-Keizer model (Young et al., 1992).
| Parameters of De Young-Keizer model | ||
|---|---|---|
| Parameter | Value | Description |
| c0 | 2.0 μM | Total [Ca2+] in terms of cytosolic vol |
| c1 | 0.185 | (ER vol)/(cytosolic vol) |
| ν1 | 6.0 s−1 | Max Ca2+ channel flux |
| ν2 | 0.11 s−1 | Ca2+ leak flux constant |
| ν3 | 0.9 μMs−1 | Max Ca2+ uptake |
| k3 | 0.1 μM | Activation constant for ATP-Ca2+ pump |
| d1 | 0.13 μM | IP3 |
| d2 | 1.049 μM | Ca2+ (inhibition) |
| d3 | 0.9434 μM | IP3 |
| d5 | 0.08234 μM | Ca2+ (activation) |
| a2 | 0.2 μMs−1 | Ca2+ (inhibition) |
| IP3 | 0.5 μM | IP3 flux |