Table 3.

Parameters of the Atri model (Atri et al., 1993).

Parameters of Atri model
Parameter	Value	Description
b	0.111	Proportion of IP3Rs spontaneously activated in the absence of bound Ca2+
V1	0.889	Proportion of IP3Rs that are activated by the binding of Ca2+
β	0.0–0.02 μMs−1	Constant rate of Ca2+ influx into the cytosol from the outside
γ	2.0 μMs−1	Maximum rate of Ca2+ pumping from the cytosol
τn	2.0 s	Time constant for the dynamics of n, the proportion of IP3Rs not closed by Ca2+
k1	0.7 μM	Constant related to the activation of a channel in response to Calcium binding
kγ	0.1 μM	[Ca2+]c at which the rate of Ca2+ pumping from the cytosol is at half-maximum
k2	0.7 μM	Constant related to the inactivation of a channel in response to Calcium binding
kflux	8.1 μMs−1	Maximum total Ca2+ flux through all IP3Rs