Table 2.
Risk of sleep disorder exposed to dry eye compared to non-dry eye.
| No. of event | |||
|---|---|---|---|
| Dry eye (N = 688413) |
Non-Dry eye (N = 688413) |
HR (95% C.I.) | |
| All duration | |||
| Sleep disorder (G47, F51.0, F51.8, F51.9) | 91,026 | 97,677 | 1.03 (1.02–1.04) |
| G47 Sleep disorders | 85,461 | 90,753 | 1.04 (1.03–1.05) |
| G47.0 Insomnia | 37,517 | 40,777 | 1.02 (1.004–1.03) |
| G47.3 Sleep apnea | 47,902 | 47,802 | 1.11 (1.10–1.13) |
|
F51.0 Insomnia not due to a substance or known physiological condition |
13,695 | 14,999 | 1.04 (1.01–1.06) |
|
F51.8 Other sleep disorders not due to a substance or known physiological condition |
657 | 459 | 1.59 (1.41–1.79) |
|
F51.9 Sleep disorder not due to a substance or known physiological condition, unspecified |
130 | 101 | 1.43 (1.10–1.85) |
| 1-yr follow-up duration | |||
| Sleep disorder (G47, F51.0, F51.8, F51.9) | 23,608 | 24,407 | 0.99 (0.97–1.01) |
| G47 Sleep disorders | 22,130 | 22,581 | 1.00 (0.98–1.02) |
| G47.0 Insomnia | 8341 | 9043 | 0.94 (0.92–0.97) |
| G47.3 Sleep apnea | 12,166 | 11,752 | 1.06 (1.03–1.09) |
|
F51.0 Insomnia not due to a substance or known physiological condition |
2234 | 2452 | 0.93 (0.88–0.99) |
|
F51.8 Other sleep disorders not due to a substance or known physiological condition |
136 | 100 | 1.39 (1.08–1.80) |
|
F51.9 Sleep disorder not due to a substance or known physiological condition, unspecified |
18 | 26 | 0.71 (0.39–1.29) |
| 2-yr follow-up duration | |||
| Sleep disorder (G47, F51.0, F51.8, F51.9) | 40,141 | 39,561 | 1.01 (0.99–1.02) |
| G47 Sleep disorders | 37,600 | 36,505 | 1.02 (1.01–1.04) |
| G47.0 Insomnia | 14,429 | 14,715 | 0.97 (0.95–1.00) |
| G47.3 Sleep apnea | 20,903 | 18,973 | 1.10 (1.07–1.12) |
|
F51.0 Insomnia not due to a substance or known physiological condition |
4262 | 4454 | 0.95 (0.91–0.99) |
|
F51.8 Other sleep disorders not due to a substance or known physiological condition |
233 | 124 | 1.87 (1.50–2.32) |
|
F51.9 Sleep disorder not due to a substance or known physiological condition, unspecified |
41 | 26 | 1.57 (0.96–2.57) |
| 5-yr follow-up duration | |||
| Sleep disorder (G47, F51.0, F51.8, F51.9) | 66,167 | 65,949 | 1.04 (1.02–1.05) |
| G47 Sleep disorders | 61,943 | 60,956 | 1.05 (1.04–1.06) |
| G47.0 Insomnia | 25,926 | 25,978 | 1.03 (1.01–1.05) |
| G47.3 Sleep apnea | 33,938 | 31,799 | 1.10 (1.09–1.12) |
|
F51.0 Insomnia not due to a substance or known physiological condition |
8545 | 8796 | 1.01 (0.98–1.04) |
|
F51.8 Other sleep disorders not due to a substance or known physiological condition |
448 | 272 | 1.70 (1.46–1.98) |
|
F51.9 Sleep disorder not due to a substance or known physiological condition, unspecified |
87 | 53 | 1.70 (1.21–2.39) |