Table 3.
Risk of sleep disorder among different subtypes of dry eye.
| Dry eye | Non-Dry eye | ||||
|---|---|---|---|---|---|
| N | No. of event | N | No. of event | HR (95% C.I.) | |
| Sjögren syndrome (M35.0) | |||||
| Sleep disorder (G47, F51.0, F51.8, F51.9) | 95,804 | 14,307 | 95,804 | 13,186 | 1.22 (1.20–1.25) |
| G47 Sleep disorders | 95,804 | 13,472 | 95,804 | 12,098 | 1.26 (1.23–1.29) |
| G47.0 Insomnia | 95,804 | 6021 | 95,804 | 5789 | 1.16 (1.12–1.21) |
| G47.3 Sleep apnea | 95,804 | 7531 | 95,804 | 6000 | 1.41 (1.37–1.46) |
| F51.0 Insomnia not due to a substance or known physiological condition | 95,804 | 2128 | 95,804 | 2201 | 1.10 (1.04–1.17) |
|
F51.8 Other sleep disorders not due to a substance or known physiological condition |
95,804 | 127 | 95,804 | 74 | 1.89 (1.42–2.52) |
|
F51.9 Sleep disorder not due to a substance or known physiological condition, unspecified |
95,804 | 25 | 95,804 | 18 | 1.59 (0.87–2.92) |
| Meibomian gland dysfunction of eyelid (H02.88) | |||||
| Sleep disorder (G47, F51.0, F51.8, F51.9) | 82,119 | 8884 | 82,119 | 12,452 | 0.98 (0.95–1.01) |
| G47 Sleep disorders | 82,119 | 8339 | 82,119 | 11,601 | 0.99 (0.96–1.02) |
| G47.0 Insomnia | 82,119 | 3253 | 82,119 | 5102 | 0.91 (0.87–0.95) |
| G47.3 Sleep apnea | 82,119 | 4899 | 82,119 | 6241 | 1.10 (1.06–1.14) |
| F51.0 Insomnia not due to a substance or known physiological condition | 82,119 | 1217 | 82,119 | 1849 | 1.04 (0.97–1.12) |
|
F51.8 Other sleep disorders not due to a substance or known physiological condition |
82,119 | 58 | 82,119 | 52 | 1.68 (1.14–2.47) |
|
F51.9 Sleep disorder not due to a substance or known physiological condition, unspecified |
82,119 | 10 | 82,119 | 15 | 0.64 (0.27–1.51) |