Table 4.
Stratification analysis of risk of sleep disorder among different groups.
| Dry eye | Non-Dry eye | ||||
|---|---|---|---|---|---|
| N | No. of event | N | No. of event | HR (95% C.I.) | |
| Age | |||||
| 20–49 | 204,626 | 22,275 | 204,626 | 25,068 | 1.02 (1.002–1.04) |
| 50–59 | 139,149 | 20,437 | 139,149 | 22,370 | 1.02 (1.003–1.04) |
| 60–69 | 183,123 | 27,343 | 183,123 | 28,260 | 1.03 (1.01–1.04) |
| ≥ 70 | 166,216 | 21,005 | 166,216 | 21,487 | 0.98 (0.96–1.00) |
| Sex | |||||
| Female | 354,024 | 44,433 | 354,024 | 47,214 | 1.03 (1.01–1.04) |
| Male | 224,134 | 30,406 | 224,134 | 33,724 | 0.99 (0.98–1.01) |
| Ethnicity | |||||
| Not Hispanic or Latino | 465,854 | 66,311 | 465,854 | 71,279 | 1.01 (1.002–1.02) |
| Hispanic or Latino | 57,015 | 7030 | 57,015 | 7098 | 0.97 (0.94–1.01) |
| Race | |||||
| White | 405,646 | 56,769 | 405,646 | 61,684 | 1.02 (1.01–1.04) |
| Black or African American | 105,759 | 15,410 | 105,759 | 15,911 | 0.99 (0.97–1.01) |
| Asian | 44,490 | 4272 | 44,490 | 4611 | 1.03 (0.99–1.07) |
| American Indian or Alaska Native | 2697 | 379 | 2697 | 379 | 1.01 (0.88–1.16) |
| Native Hawaiian or Other Pacific Islander | 6577 | 1525 | 6577 | 1210 | 1.23 (1.14–1.33) |
| Hypertensive diseases | 130,935 | 25,953 | 130,935 | 23,993 | 1.10 (1.08–1.12) |
| Hyperlipidemia | 112,579 | 21,496 | 112,579 | 20,324 | 1.11 (1.09–1.13) |
| Diabetes mellitus | 62,916 | 12,115 | 62,916 | 11,729 | 1.05 (1.03–1.08) |
| Overweight and obesity | 30,832 | 7100 | 30,832 | 6549 | 1.06 (1.02–1.10) |
| Ischemic heart diseases | 24,890 | 5315 | 24,890 | 4622 | 1.14 (1.09–1.18) |
| Heart failure | 8664 | 1974 | 8664 | 1652 | 1.12 (1.05–1.20) |
| Tobacco use | 4099 | 820 | 4099 | 720 | 1.17 (1.05–1.29) |
| Alcohol related disorders | 3480 | 681 | 3480 | 587 | 1.16 (1.04–1.30) |
| Rheumatoid arthritis | 11,609 | 2227 | 11,609 | 2130 | 1.03 (0.97–1.09) |
| Chronic obstructive pulmonary disease | 9195 | 2235 | 9195 | 2017 | 1.09 (1.02–1.15) |
| Chronic fatigue, unspecified | 1904 | 430 | 1904 | 413 | 1.10 (0.96–1.26) |
| Chronic pain, not elsewhere classified | 24,483 | 4898 | 24,483 | 4727 | 1.03 (0.99–1.08) |
| Hypnotics and sedatives | 48,799 | 9213 | 48,799 | 8993 | 0.99 (0.96–1.01) |
| Benzodiazepine derivatives | 22,860 | 4632 | 22,860 | 4665 | 1.02 (0.98–1.06) |
| Anticholinergics | 11,000 | 2490 | 11,000 | 2262 | 1.06 (1.003–1.12) |