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. 2025 Apr 11;15:12367. doi: 10.1038/s41598-025-97396-3

Table 4.

Stratification analysis of risk of sleep disorder among different groups.

Dry eye Non-Dry eye
N No. of event N No. of event HR (95% C.I.)
Age
20–49 204,626 22,275 204,626 25,068 1.02 (1.002–1.04)
50–59 139,149 20,437 139,149 22,370 1.02 (1.003–1.04)
60–69 183,123 27,343 183,123 28,260 1.03 (1.01–1.04)
≥ 70 166,216 21,005 166,216 21,487 0.98 (0.96–1.00)
Sex
Female 354,024 44,433 354,024 47,214 1.03 (1.01–1.04)
Male 224,134 30,406 224,134 33,724 0.99 (0.98–1.01)
Ethnicity
Not Hispanic or Latino 465,854 66,311 465,854 71,279 1.01 (1.002–1.02)
Hispanic or Latino 57,015 7030 57,015 7098 0.97 (0.94–1.01)
Race
White 405,646 56,769 405,646 61,684 1.02 (1.01–1.04)
Black or African American 105,759 15,410 105,759 15,911 0.99 (0.97–1.01)
Asian 44,490 4272 44,490 4611 1.03 (0.99–1.07)
American Indian or Alaska Native 2697 379 2697 379 1.01 (0.88–1.16)
Native Hawaiian or Other Pacific Islander 6577 1525 6577 1210 1.23 (1.14–1.33)
Hypertensive diseases 130,935 25,953 130,935 23,993 1.10 (1.08–1.12)
Hyperlipidemia 112,579 21,496 112,579 20,324 1.11 (1.09–1.13)
Diabetes mellitus 62,916 12,115 62,916 11,729 1.05 (1.03–1.08)
Overweight and obesity 30,832 7100 30,832 6549 1.06 (1.02–1.10)
Ischemic heart diseases 24,890 5315 24,890 4622 1.14 (1.09–1.18)
Heart failure 8664 1974 8664 1652 1.12 (1.05–1.20)
Tobacco use 4099 820 4099 720 1.17 (1.05–1.29)
Alcohol related disorders 3480 681 3480 587 1.16 (1.04–1.30)
Rheumatoid arthritis 11,609 2227 11,609 2130 1.03 (0.97–1.09)
Chronic obstructive pulmonary disease 9195 2235 9195 2017 1.09 (1.02–1.15)
Chronic fatigue, unspecified 1904 430 1904 413 1.10 (0.96–1.26)
Chronic pain, not elsewhere classified 24,483 4898 24,483 4727 1.03 (0.99–1.08)
Hypnotics and sedatives 48,799 9213 48,799 8993 0.99 (0.96–1.01)
Benzodiazepine derivatives 22,860 4632 22,860 4665 1.02 (0.98–1.06)
Anticholinergics 11,000 2490 11,000 2262 1.06 (1.003–1.12)