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. 2025 Apr 4;17(7):1221. doi: 10.3390/cancers17071221

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© 2025 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The immunohistochemical staining of whole brain tumour specimens from patients with glioblastoma for the expression of the HER-family members. Formalin-fixed paraffin-embedded tumour sections were stained with primary mAb as described under Materials and Methods. (A) EGFR 3+, cytoplasmic/membranous, ×200 magnification (B) HER2 2+ cytoplasmic, ×200 magnification (C) HER3 2+ cytoplasmic, ×200 magnification (D) HER4 2+ cytoplasmic, ×200 magnification (E) EGFRvIII 2+ cytoplasmic, (F) CD44 3+ membranous, (G) CD109 1+ cytoplasmic, ×200 magnification.