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. 2025 Apr 2;14(7):534. doi: 10.3390/cells14070534
15d-PGJ2 15-deoxy-Δ12,14-prostaglandin J2
5-FU fluorouracil
AF activation function
AgRC agonist–receptor complex
AnRC antagonist–receptor complex
AIF apoptosis-inducing factor
ALT alanine aminotransferase
ALPI alkaline phosphatase
AMPK AMP-activated protein kinase
AP1 activator protein 1
BAX BCL2-associated X protein
Bcl B-cell lymphoma proteins (Bcl-2 and Bcl-xL)
BRAF B-rapidly accelerated fibrosarcoma
BRCA1 breast cancer gene 1
cAMP cyclic adenosine monophosphate
CAF cancer-associated fibroblasts
CASP1 caspase 1
CAT catalase
CBP CREB-binding protein
CCL2 C-C motif chemokine ligand 2
CCND1 cyclin D1
CD complex of differentiation
CDK5 cyclin-dependent kinase 5
c-FLIP flice-inhibitory protein
CHK2 checkpoint kinase 2
CGZ ciglitazone
CNS central nervous system
CCND1 cyclin D1
COX2 cyclooxygenase 2
CTL cytotoxic lymphocyte
CTLA cytotoxic T-lymphocyte antigen
CXCL12 C-X-C motif chemokine ligand 12
DBD DNA-binding domain
DC dendritic cell
DHA docosahexanoic acid
DOPA 3,4-dihydroxyphenylalanine
DOPA enzyme tyrosine hydroxylase
DR death receptor
DTIC dacarbazine
ECM extracellular matrix
EFZ multidrug resistance 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
eIF2 eukaryotic initiation factor 2
EPA eicosopentanoic acid
ERK1/2 extracellular signal-regulated kinases ½
FABP4 fatty acid-binding protein 4
FAK focal adhesion kinase
FDA Food and Drug Administration
FOS this protein name originates from Finkel–Biskis–Jinkins (FBJ) murine osteosarcoma virus
GPX glutathione peroxidase
GSK-3β glycogen synthase kinase-3β
HCC hepatocellular carcinoma
HDAC3 histone deacetylase 3
HIF1 α hypoxia-inducible factor 1α
HMOX1 heme oxygenase-1
IFNG interferon γ
IGF1 insulin-like growth factor 1
IGFBP3 insulin growth factor-binding protein 3
IGF1 insulin growth factor 1
IKK-α inhibitor of nuclear factor κB kinase subunit α
JNK c-Jun N-terminal kinase
JUN this protein name originates from “ju-nana”, the Japanese word for “17”,じゅうなな, (e.g., a viral oncogene v-jun means the seventeenth viral oncogene in English)
KLRG1 killer cell lectin-like receptor subfamily G member 1
LAG3 lymphocyte-activation gene 3
LBD ligand-binding domain
LC-PUFA long-chain polyunsaturated fatty acid
LXR liver X receptor
MAPK mitogen-activated protein kinase
MC1R melanocortin-1 receptor
MCAD1 medium-chain acyl-CoA dehydrogenase
MDR1 multidrug resistance 1
MDSC myeloid-derived suppressor cell
MHC1 major histocompatibility complex class I
MITF microphthalmia-associated transcription factor
α-MSH α-melanocyte-stimulating hormone
mTOR mechanistic target of rapamycin
NCoA nuclear receptor coactivator
NCoR nuclear receptor corepressor
NFκB nuclear factor κB
NRF2 nuclear factor erythroid 2-related factor 2
NSCLC non-small cell lung cancer
NYHA New York Heart Association
Octa 2,4,6-octatrienoic acid
O-GlcNAc β-O-linked N-acetylglucosamine
p70S6K p70 ribosomal S6 kinase
PDGF platelet-derived growth factor
PDK4 pyruvate dehydrogenase kinase 4
PD-L1 programmed death ligand 1
PERK protein kinase RNA-like endoplasmic reticulum kinase
PGC-1α PPAR-γ coactivator-1α
PGC-1β PPAR-γ coactivator-1β
PGZ pioglitazone
PI3K phosphoinositide 3-kinase
PKA protein kinase A
PKB protein kinase B
PKC protein kinase C
PKR protein kinase RNA-activated
PLA2 phospholipase A2
PLC phospholipase C
PPAR-α peroxisome proliferator-activated receptor α
PPAR-β/δ peroxisome proliferator-activated receptor β/δ
PPAR-γ peroxisome proliferator-activated receptor γ
PPRE peroxisome proliferator response element
PTEN phosphatase and tensin homolog deleted on chromosome 10
PUFA polyunsaturated fatty acid
RB1 retinoblastoma 1
RGZ rosiglitazone
ROS reactive oxygen species
RXR- α retinoid X receptor α
SHC Src homology and collagen
SMAD2 mothers against decapentaplegic homolog 2
SMRT silencing mediator of retinoid and thyroid hormone receptors
SNP single-nucleotide polymorphism
SOD superoxide dismutase
SRC sarcoma family member
STAT3 signal transducer and activator of transcription 3
T2D type 2 diabetes
TAM tumor-associated macrophage
TetO tetracycline operator
TGF-β transforming growth factor-β
TIM3 T-cell immunoglobulin and mucin domain-3
TME tumor microenvironment
TNF-α tumor necrosis factor-α
TP53 tumor protein p53
TRAIL TNF-related apoptosis-inducing ligand
Treg regulatory T cell
TRPM1 transient receptor potential melastatin 1
TRP1 tyrosinase-related protein-1
TRP2 tyrosinase-related protein-2
TZD thiazolidinedione
TYR tyrosinase
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D receptor
VEGF vascular endothelial growth factor
VILL1 villin 1
WNT wingless-related integration site