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. 2005 Aug 23;390(Pt 2):521–528. doi: 10.1042/BJ20050439

Figure 1. 5′-Flanking region of human GSS.

Figure 1

(A) Sequence of the 5′-flanking region of human GSS. Two primers (see the Materials and methods section) were used for 5′-RACE to determine the transcriptional start site, indicated by the forward arrow. TFSearch and MatInspector databases identified potential transcription factor-binding sites, denoted in bold above the sequence and underlined. (B) Comparison of the human and rat GSS promoter using NCBI blast analysis indicated only three areas that shared a high degree of homology (>80%). These regions included −2211/−2170, −1767/−1707 and −112/−48 of human GSS corresponding to −1053/−1011, −936/−877 and −110/−47 of the rat GSS respectively. Putative transcription factor-binding sites present in these regions are shown.