Table 1. DSC data showing the chain melting transition.
Tm, transition temperature; ΔH, calorimetric enthalpy (1 kcal=4.184 kJ). The all-D isomer of the peptide is indicated by the lowercase letters (lwyik; LWYIK refers to the all-L ismoer of the peptide).
| Sample composition | |||||
|---|---|---|---|---|---|
| Cholesterol | ent-Cholesterol | ||||
| SOPC:sterol (molar ratio) | Peptide (all N-acetyl amides) | Tm (°C) | ΔH (kcal/mol) | Tm (°C) | ΔH (kcal/mol) |
| 7:3 | None | 3.9 | 0.52 | 4.8 | 0.54 |
| 7:3 | 10% LWYIK | 4.0 | 1.1 | 4.5 | 0.57 |
| 7:3 | 15% LWYIK | 3.6 | 1.2 | 4.7 | 0.62 |
| 7:3 | 10% lwyik | 4.2 | 1.0 | 4.1 | 0.80 |
| 7:3 | 15% lwyik | 4.1 | 1.3 | 3.9 | 0.85 |
| 6:4 | None | 4.7 | 0.1 | 4.2 | 0.15 |
| 6:4 | 10% LWYIK | 4.8 | 0.3 | 3.9 | 0.35 |
| 6:4 | 15% LWYIK | 4.0 | 0.5 | 4.5 | 0.35 |
| 6:4 | 10% lwyik | 4.8 | 0.4 | 1.5 | 0.16 |
| 6:4 | 15% lwyik | 4.9 | 0.6 | 3.7 | 0.29 |