Table 3.

Descriptive data for the primary outcomes (VAS; KOOS-Pain; KOOS-Symptoms) for all four time points (mean ± SD).

VAS	pre	6 Months	12 Months	24 Months
MACI	3.5 ± 2.1	2.5 ± 1.9	2.2 ± 2.0 *	2.1 ± 1.7 *
AMIC	2.8 ± 2.1	1.6 ± 1.3	1.8 ± 1.9	1.7 ± 2.2
MCI	4.6 ± 2.5	1.7 ± 1.7 *	1.5 ± 1.3 **	2.0 ± 1.6 *
KOOS-Pain
MACI	65.28 ± 17.82	71.18 ± 13.18	76.50 ± 14.81 *	80.56 ± 13.08 *
AMIC	67.41 ± 15.51	80.93 ± 12.89 *	80.37 ± 11.57 *	80.74 ± 18.85 *
MCI	62.34 ± 19.51	81.77 ± 13.91 *	80.90 ± 12.98 *	83.89 ± 12.91 **
KOOS-Symptoms
MACI	63.97 ± 15.37	67.22 ± 9.44	71.96 ± 12.76 *	74.60 ± 14.30 *
AMIC	64.86 ± 13.10	73.50 ± 11.95	72.13 ± 10.42	72.39 ± 14.34
MCI	60.81 ± 13.76	76.22 ± 12.44 *	74.95 ± 14.43 *	83.97 ± 11.05 **

* significant effect of time p ≤ 0.005; ** high significant effect of time p ≤ 0.001.