a-CGH	array comparative genomic hybridization
ASD	autism spectrum disorder
MRI	magnetic resonance imaging
MDT	multi-disciplinary team
EEG	electroencephalogram
ADOS	Autism Diagnostic Observation Schedule
ADI-R	Autism Diagnostic Interview-Revised (ADI-R)
DSM 5TR	Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision
MSEL	Mullen Scales of Early Learning (MSEL)
CDI	MacArthur–Bates Communicative Developmental Inventory
WHO	World Health Organization
CDC	Centers for Disease Control and Prevention (CDC)
mTOR	mammalian target of rapamycin
MECP2	methyl-CpG-binding protein 2
CNS	central nervous system (CNS)
GI	gastrointestinal tract
SITBS	self-injurious thoughts and behaviors
C-SSRS	Columbia-Suicide Severity Rating Scale
ADHD	attention-deficit/hyperactivity disorder
IDD	intellectual developmental disorder
IQ	intelligence quotient
PI3K	phosphoinositide 3-kinases
NRXN	neurexins
NLGN	neuroligin
OCD	obsessive-compulsive disorder
FXS	Fragile X syndrome
DS	Down syndrome
NF1	neurofibromatosis type I
TSC	tuberous sclerosis complex
CPK	creatine phosphokinase
ED	emergency department
SIB	self-injurious behavior
NaSSA	noradrenergic and specific serotonergic antidepressants
SSRIs	selective serotonin reuptake inhibitors
ILAE	International League Against Epilepsy (ILAE)
GGE	genetic generalized epilepsy
FE	focal epilepsy (FE)
FMTLE	mesial temporal lobe epilepsy
ADLTE	autosomal dominant lateral temporal epilepsy
ADNFLE	autosomal dominant nocturnal frontal lobe epilepsy
HS	hippocampal sclerosis
FS	febrile seizures
LGI1	leucine-rich glioma-inactivated 1 (LGI1)
nAChR	neuronal nicotinic acetylcholine receptor
LMICs	middle-income countries
HIV	human immunodeficiency virus
BBB	Blood–brain barrier
GABA	gamma-aminobutyric acid, γ-aminobutyric acid
NMDA-R	N-methyl-D-aspartate receptor
AMPA	α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
mGLuR5	metabotropic glutamate receptor 5 (mGluR5),
GAD65	glutamic acid decarboxylase 65 (GAD65),
ANNA-1	antineuronal nuclear antibody type 1 (ANNA-1),
IL-1R/TLR	IL-1 receptor/toll-like receptor
PAMP	pathogen-associated molecular patterns
DAMPs	damage-associated molecular patterns
COX2	cyclooxygenase-2
TGF-β/Smad	transforming growth factor-β/small mothers against decapentaplegic
HMGB1	high-mobility group box-1 (HMGB1)
SUDEP	sudden death in wpilepsy
SCN1A	sodium voltage-gated channel alpha subunit 1
GABA	4-aminobutanoic acid
CT	computed tomography
SPECT	single-photon emission computed tomography
SIADH	syndrome of inappropriate secretion of antidiuretic hormone
CBZ	carbamazepine
CRMP2	collapsing response mediator protein 2
SV2A	synaptic vesicle glycoprotein 2A
AED	antiepileptic drugs
RTT	Rett syndrome
UBE3A	ubiquitin-protein ligase E3A (UBE3A,
ACC	agenesis of the corpus callosum
SHANk3	multiple ankyrin repeat domains 3
ARX	aristaless-related homeobox
FOXP2	forkhead box P2
SCN1A	sodium voltage-gated channel alpha aubunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN8A	sodium voltage-gated channel alpha subunit 8
KCNB1	potassium voltage-gated channel subfamily B member 1
CACNA1A	calcium voltage-gated channel subunit alpha1 A
SHANK3	SH3 and multiple ankyrin repeat domains 3
CDKL5	cyclin-dependent kinase-like 5
STXBP1	syntaxin binding protein 1
NRXN1	neurexin 1
PCDH19	protocadherin 19
CASK	calcium/calmodulin-dependent serine protein kinase
SYNGAP1	synaptic Ras GTPase activating protein 1
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
PACS2	hosphofurin acidic cluster sorting protein 2
ACTL6B	actin like 6B
MEF2C	myocyte enhancer factor 2C
FOXG1	forkhead box G1
VAP	valproic acid
TCAs	tricyclic antidepressants (TCAs)
EKG	electrocardiogram
KS	Klinefelter syndrome
ADEM	acute disseminated encephalomyelitis