TABLE 2.

Characteristics of eight H. pylori isolates with high in vitro apoptosis scores from Japanese patients with GU

Strain	Patient age (yr)/sexa	Apoptosis scoreb	Genotype			HP0638 frame status	IL-8 induction (pg/ml)c	P-Tyrd
			cagA	vacAs	vacAm
98-38	51/M	5.8	+	slc	ml	In	817	+
98-35	42/M	4.8	+	slc	ml	In	1,929	+
98-41	46/M	4.8	+	slc	ml	In	944	+
98-39	48/M	4.7	+	slc	ml	In	954	+
98-36	46/M	4.4	+	slc	ml	In	287	+
98-37	50/F	4.4	+	slc	ml	In	287	+
98-32	36/M	4.1	+	slc	ml	In	151	−
98-40	65/M	4.1	+	slc	ml	In	2,590	+

^aM, male; F, female.

^bFold increase in DNA fragmentation of AGS cells relative to control cells.

^cMeans from two replicate assays.

^dPresence of tyrosine-phosphorylated CagA protein within epithelial cells, determined as described in Materials and Methods (+, present; −, absent).