TABLE 2.
Mean levels of CRP and SAA in serum as measured by ELISA
Group no. | Subject group | No. of subjects | Mean level (μg/ml)a in serum ± SE
|
|
---|---|---|---|---|
CRP | SAA | |||
1 | PD− CVD− | 26 | 1.68 ± 1.42 | 15.92 ± 3.36 |
2 | PD+ CVD− | 20 | 2.40 ± 1.89 | 11.15 ± 4.58 |
3 | PD− CVD+ | 18 | 3.35 ± 1.56 | 19.44 ± 3.70 |
4 | PD+ CVD+ | 16 | 8.58 ± 1.74 | 27.75 ± 4.13 |
Overall P of <0.05 for CRP values (P = 0.0162) and SAA values (P = 0.389). Specific post hoc comparisons were as follows for CRP: P = 0.0029 (groups 1 and 4), 0.0192 (groups 2 and 4), and 0.0282 (groups 3 and 4). Specific post hoc comparisons were as follows for SAA: P = 0.0294 (groups 2 and 3) and 0.0090 (groups 2 and 4). A summary table of APP levels was determined by ELISA analysis. The data were analyzed using by ANCOVA and reported as the group mean ± SE, with an adjustment for smoking. Normal levels as reported by the kit manufacturers were as follows: CRP range, 0.6 to 1.9 μg/ml; and SAA range, 1.0 to 10.0 μg/ml (reported mean, 3.0 to 4.0 μg/ml).