TABLE 3.
Mean levels of AAG, ACT, and ceruloplasmin as measured by RID assay
| Group no. | Subject group | No. of subjects | Mean level (mg/liter)a in serum ± SE
|
||
|---|---|---|---|---|---|
| AAG | ACT | Ceruloplasmin | |||
| 1 | PD− CVD− | 26 | 943.7 ± 110.8 | 563.4 ± 44.2 | 308.7 ± 54.3 |
| 2 | PD+ CVD− | 20 | 854.6 ± 134.8 | 698.5 ± 51.3 | 311.7 ± 59.4 |
| 3 | PD− CVD+ | 18 | 872.5 ± 134.4 | 529.4 ± 56.8 | 731.0 ± 59.4 |
| 4 | PD+ CVD+ | 16 | 1365.8 ± 145.8 | 589.4 ± 56.7 | 338.1 ± 67.5 |
Overall P values were as follows: AAG, 0.0408 (statistically significant); ACT, 0.1273; and ceruloplasmin, 0.0001 (statistically significant). Specific P values were as follows for AAG: P = 0.0273 (groups 1 and 4), 0.0109 (groups 2 and 4), and 0.0158 (groups 3 and 4). Specific P values were as follows for ceruloplasmin: P = 0.0001 (groups 1 and 3, 2 and 3, and 3 and 4). The mean and SE of AAG, ACT, and ceruloplasmin levels of subjects in the four groups were determined by RID assay. The data were analyzed by using ANCOVA and reported as the group mean ± the SE, with an adjustment for smoking. Normal levels as reported by the kit manufacturers were as follows: AAG range, 512 to 869 mg/liter (mean, 683 mg/liter), ACT range, 356 to 596 mg/liter (mean, 476 mg/liter) and ceruloplasmin range, 230 to 370 mg/liter (mean, 292 mg/liter).