TABLE 4.
Mean levels of soluble CAM in serum as measured by ELISA
| Group no. | Subject group | No. of subjects | Mean level (ng/ml)a in serum ± SE
|
|
|---|---|---|---|---|
| sVCAM | sICAM | |||
| 1 | PD− CVD− | 26 | 896.5 ± 130.0 | 289.1 ± 24.8 |
| 2 | PD+ CVD− | 20 | 953.0 ± 188.9 | 315.9 ± 36.0 |
| 3 | PD− CVD+ | 18 | 1,538.1 ± 152.5 | 333.3 ± 29.1 |
| 4 | PD+ CVD+ | 16 | 1,334.9 ± 166.3 | 293.0 ± 31.7 |
a
Overall P values were as follows: sVCAM, 0.0054 (P < 0.05); and sICAM, 0.6495. For post hoc comparisons for sVCAM, P = 0.0015 (groups 1 and 3), 0.0399 (groups 1 and 4), and 0.0257 (groups 2 and 3). A summary table of sCAM levels was determined by ELISA analysis. The data were analyzed by using ANCOVA and reported as the group mean ± SE, with an adjustment for smoking. Normal levels as reported by the kit manufacturers were as follows: sVCAM range, 395 to 714 ng/ml (mean, 553 ng/ml); and sICAM range, 114.7 to 306.4 ng/ml (mean, 210.6 ng/ml).