Table 2.

Magnetocatalytic hydrogenation of various amides using ICNPs@Pt/Al₂O₃

Subs. #	Subs.	μ0H (mT)	Time (h)	Conversion (%)	Prod. #	Prod.	Yield (%)
1		72	4	>99	1a		>99 (95)
2		72	4	>99	2a		>99
3		72	4	>99	3a		50
					3b		50
4		72	4	>99	4a		>99
5		72	4	>99	5a		>99
6		72	4	>99	5a		>99 (89)
7		72	4	75	7a		48
					7b		17
					7c		8
8		72	4	>99	8a		>99
9		60	2	20	9a		20
			4	48	9a		12
					9b		36
			16	>99	9b		>99
10		45	8	>99	10a		81
					9b		19
11		60	16	>99	11a		>99
12		72	4	>99	12b		>99
		60	16	98	12a		95a
13		60	18	>99	13a		54
					13b		30
					13c		16
14		72	4	39	14a		39
15		72	4	>99	15a		>99
16		72	8	>99	15a		>99
17		72	4	>99	15a		>99

Reaction conditions: 1 (12.9 mg, 0.10 mmol), ICNPs@Pt/Al₂O₃ (35.0 mg, 1.26 µmol Pt), decalin (0.5 mL), H₂ (3 bar). GC Products yields were determined relative to an internal standard of tetradecane and isolated yields are given in parentheses. For isolation: 0.4 mmol of substrate and 16 h. For substrate 11: mixture of dioxane and decalin as solvent to ensure good substrate solubility.

^aRest is 3% tetrahydroindole.