Figure 2.

Haplotypes consisting of 14 SNPs—6 from our previous risk haplotype and 8 newly selected ones—of four homozygous individuals. Individuals homozygous for one of the haplotypes identified in our previous study (the corresponding SNPs are indicated in plain typeface) were typed for eight new SNPs (indicated in bold typeface). They were also homozygous for all eight new SNPs. Risk alleles are in dark gray boxes; nonrisk alleles are in light gray boxes. freq T = frequency of transmitted haplotype; freq NT = frequency of nontransmitted haplotype.