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. 2025 Mar 31;16:1559484. doi: 10.3389/fneur.2025.1559484

Table 3.

Baseline of laboratory and biochemical characteristics.

Variable Ruptured (n = 349) Non-ruptured (n = 501) p
WBC count (10^9/L) 10.31 ± 4.55 7.37 ± 2.85 <0.001
RBC count (10^12/L) 4.44 ± 0.52 4.49 ± 0.58 0.169
MCV (fL) 90.12 ± 5.84 91.13 ± 5.64 0.012
MCHC (g/L) 334.07 ± 11.95 334.40 ± 11.41 0.691
MCH (pg) 30.14 ± 2.46 30.50 ± 2.24 0.032
RDW (%) 13.08 ± 1.30 12.90 ± 0.93 0.023
Lymphocyte count (10^9/L) 1.82 ± 1.19 1.92 ± 0.81 0.186
Monocyte count (10^9/L) 0.53 ± 0.25 0.50 ± 0.21 0.061
Neutrophil count (10^9/L) 7.85 ± 4.47 4.79 ± 2.61 <0.001
Hematocrit (%) 39.96 ± 4.78 40.81 ± 4.81 0.011
Eosinophil percentage (%) 1.10 ± 1.49 2.12 ± 1.89 <0.001
Basophil percentage (%) 0.28 ± 0.26 0.39 ± 0.27 <0.001
Hemoglobin (g/L) 133.66 ± 17.87 136.50 ± 17.00 0.02
Platelet count (10^9/L) 225.88 ± 62.36 226.43 ± 63.54 0.9
MPV (fL) 9.89 ± 1.24 10.16 ± 1.21 0.002
PDW (%) 14.34 ± 2.47 13.36 ± 2.78 <0.001
Plateletcrit (%) 0.22 ± 0.06 0.23 ± 0.06 0.231
ALT (U/L) 26.98 ± 21.60 28.23 ± 46.06 0.595
Total bilirubin (μmol/L) 11.79 ± 5.75 12.92 ± 8.05 0.017
Total protein (g/L) 73.09 ± 8.23 71.38 ± 6.97 0.002
Creatinine (μmol/L) 78.99 ± 72.79 65.80 ± 27.75 <0.001
Potassium (mmol/L) 3.65 ± 0.53 3.86 ± 0.42 <0.001
Chloride (mmol/L) 103.77 ± 3.59 104.48 ± 2.77 0.002
Sodium (mmol/L) 139.36 ± 3.32 140.04 ± 2.70 0.002
Total calcium (mmol/L) 2.25 ± 0.13 2.28 ± 0.10 <0.001
LDH (U/L) 205.97 ± 60.65 186.87 ± 54.57 <0.001
Glucose (mmol/L) 7.74 ± 3.13 6.81 ± 2.82 <0.001
PT-INR 1.02 ± 0.15 1.02 ± 0.18 0.956
PT (s) 11.25 ± 1.73 11.24 ± 1.98 0.899
PT activity (%) 106.88 ± 14.29 107.92 ± 16.01 0.319
TT (s) 15.89 ± 3.80 16.38 ± 6.30 0.162
TT ratio 1.06 ± 0.22 1.06 ± 0.41 0.851
APTT (s) 29.78 ± 10.51 30.85 ± 4.60 0.073
Fibrinogen (g/L) 3.16 ± 0.84 3.31 ± 0.84 0.007
D-dimer (mg/L) 336 (167, 758) 172 (92, 314) <0.001
WBC count (10^9/L) 10.31 ± 4.55 7.37 ± 2.85 <0.001
RBC count (10^12/L) 4.44 ± 0.52 4.49 ± 0.58 0.169
MCV (fL) 90.12 ± 5.84 91.13 ± 5.64 0.012
MCHC (g/L) 334.07 ± 11.95 334.40 ± 11.41 0.691
MCH (pg) 30.14 ± 2.46 30.50 ± 2.24 0.032
RDW (%) 13.08 ± 1.30 12.90 ± 0.93 0.023

WBC, white blood cell; RBC, red blood cell; MCV, mean corpuscular volume; MCHC, mean corpuscular hemoglobin concentration; MCH, mean corpuscular hemoglobin; RDW, red cell distribution width; MPV, mean platelet volume; PDW, platelet distribution width; ALT, alanine aminotransferase; LDH, lactate dehydrogenase; PT-INR, prothrombin time-international normalized ratio; PT, prothrombin time; TT, thrombin time; APTT, activated partial thromboplastin time.